Figure 9.

Partial sequence alignment of 6 JHE’s. Sequence alignments showing those portions containing all residues that line the active site pocket of four lepidopteran (top 4) a coleopteran and a dipteran JHE. Absolutely conserved residues are shown in red type with yellow background. Residues conserved in at least 3 of the 6 are shown in blue type with light blue background. Blocks of residues of similar kind are shown black type with green background. Residues showing no conservation are shown in black type with a white background. Number reflects the numbering of JHE. Catalytic residues are indicated with a blue dot, and residues that directly form the active site are indicated with a red dot. Secondary structure of MsJHE is indicated above the alignments.