Table 4. Results of the logistic regression analysis on individual factors related to Cd-induced renal tubular damage.
Region | Effect markers | Explanatory variables5 | 84th cutoff1 | 90th cutoff2 |
OR3 (95% CI4) | OR3 (95% CI4) | |||
CA | U-β2M (µg/g cr) | U-Cd (µg/g cr) | 1. (1.011, 1.100) | 1.056* (1.008, 1.107) |
Age (years) | 1.040 (0.986, 1.096) | 1.014 (0.952, 1.080) | ||
U-NAG (U/g cr) | U-Cd (µg/g cr) | 1.095** (1.050, 1.143) | 1.097** (1.050, 1.145) | |
Age (years) | 0.993 (0.946, 1.041) | 0.992 (0.940, 1.046) | ||
CB | U-β2M (µg/g cr) | U-Cd (µg/g cr) | 1.197** (1.124, 1.274) | 1.156** (1.095, 1.220) |
Age (years) | 1.003 (0.949, 1.060) | 0.991 (0.932, 1.054) | ||
U-NAG (U/g cr) | U-Cd (µg/g cr) | 1.074** (1.024, 1.126) | 1.075** (1.019, 1.135) | |
Age (years) | 1.008 (0.949, 1.070) | 1.063 (0.985, 1.148) |
Cut-off values of U-β2M or U-NAG were defined as the 84th or 90th percentile values, which were calculated in subjects from Cd-non-polluted areas.
OR: Odds ratio.
CI: Confidence interval.
Explanatory variables were used as continuous variables.
**P<0.01, *P<0.05.
CA, county A; CB, county B; U-β2M, urinary level of β2-microglobulin; U-NAG, urinary level of N-acetyl-β-D-glucosaminidase; U-Cd, urinary level of cadmium.