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. 2014 Dec 23;9(12):e115794. doi: 10.1371/journal.pone.0115794

Table 6. Prevalence of hyper-U-β2M and hyper-U-NAG corresponding to U-Cd intervals among subjects from county A (CA) and county B (CB) at different cadmium exposure levels1.

U-Cd intervals (µg/g cr) 2 CA CB
Hyper-U-NAG Hyper-U-β2M Hyper-U-NAG Hyper-U-β2M
Median of U-Cd (µg/g cr) +/− % +/− % Median of U-Cd (µg/g cr) +/− % +/− %
<Q1 1.44 8/59 11.94 3/64 4.08 0.72 2/53 3.64 2/53 3.64
Q1–Q2 3.43 5/63 7.35 6/62 6.67 1.72 6/49 10.91 8/47 14.55
Q2–Q3 5.97 11/56 16.42 10/57 17.39 3.80 3/53 5.36 8/48 14.28
>Q3 13.80 24/43 35.82 12/55 15.09 12.36 12/43 21.82 27/28 49.10
Total 4.47 48/221 17.84 31/238 11.52 2.86 23/198 10.41 45/176 20.36
Linear trend test χ2 = 14.876, P<0.001 χ2 = 7.055, P = 0.008 χ2 = 7.015, P = 0.008 χ2 = 31.194, P<0.001
1

The 90th percentiles of U-β2M and U-NAG of the control group were assumed as the thresholds of hyper-U-β2M and hyper-U-NAG, respectively.

2

U-Cd intervals were divided according to the three corresponding quartiles (i.e., Q1 = 2.38 µg/g cr, Q2 = 4.47 µg/g cr, and Q3 = 8.59 µg/g cr in CA; and Q1 = 1.16 µg/g cr, Q2 = 2.86 µg/g cr, and Q3 = 6.88 µg/g cr in CB).

U-β2M, urinary level of β2-microglobulin; U-NAG, urinary level of N-acetyl-β-D-glucosaminidase; U-Cd, urinary level of cadmium.