Table 6. Prevalence of hyper-U-β2M and hyper-U-NAG corresponding to U-Cd intervals among subjects from county A (CA) and county B (CB) at different cadmium exposure levels1.
U-Cd intervals (µg/g cr) 2 | CA | CB | ||||||||
Hyper-U-NAG | Hyper-U-β2M | Hyper-U-NAG | Hyper-U-β2M | |||||||
Median of U-Cd (µg/g cr) | +/− | % | +/− | % | Median of U-Cd (µg/g cr) | +/− | % | +/− | % | |
<Q1 | 1.44 | 8/59 | 11.94 | 3/64 | 4.08 | 0.72 | 2/53 | 3.64 | 2/53 | 3.64 |
Q1–Q2 | 3.43 | 5/63 | 7.35 | 6/62 | 6.67 | 1.72 | 6/49 | 10.91 | 8/47 | 14.55 |
Q2–Q3 | 5.97 | 11/56 | 16.42 | 10/57 | 17.39 | 3.80 | 3/53 | 5.36 | 8/48 | 14.28 |
>Q3 | 13.80 | 24/43 | 35.82 | 12/55 | 15.09 | 12.36 | 12/43 | 21.82 | 27/28 | 49.10 |
Total | 4.47 | 48/221 | 17.84 | 31/238 | 11.52 | 2.86 | 23/198 | 10.41 | 45/176 | 20.36 |
Linear trend test | χ2 = 14.876, P<0.001 | χ2 = 7.055, P = 0.008 | χ2 = 7.015, P = 0.008 | χ2 = 31.194, P<0.001 |
The 90th percentiles of U-β2M and U-NAG of the control group were assumed as the thresholds of hyper-U-β2M and hyper-U-NAG, respectively.
U-Cd intervals were divided according to the three corresponding quartiles (i.e., Q1 = 2.38 µg/g cr, Q2 = 4.47 µg/g cr, and Q3 = 8.59 µg/g cr in CA; and Q1 = 1.16 µg/g cr, Q2 = 2.86 µg/g cr, and Q3 = 6.88 µg/g cr in CB).
U-β2M, urinary level of β2-microglobulin; U-NAG, urinary level of N-acetyl-β-D-glucosaminidase; U-Cd, urinary level of cadmium.