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. Author manuscript; available in PMC: 2014 Dec 23.
Published in final edited form as: Immunity. 2012 Dec 6;37(6):1009–1023. doi: 10.1016/j.immuni.2012.08.027

Figure 7. NLRP1 deficiency enhances hematopoietic responses to LCMV.

Figure 7

(A) Peripheral blood parameters of LCMV-infected mice at steady state (day 0) and day 4 and 11 post-infection with LCMV (clone 13). *p<0.05, mean ± SEM, n=4–7. (B) Weight of mice after infection with LCMV. *p<0.05, mean ± SEM, n=6. (C) Spleen weight 12 days after LCMV infection. *p<0.05, mean ± SEM, n=6. (D) Total nucleated cells in the bone marrow and spleen 12 days after LCMV infection. *p<0.05, mean ± SEM, n=6. (E) Tetramer-positive (LCMV-specific) CD8+ T cells in the spleen 12 days post LCMV-infection. *p<0.05, mean ± SEM, n=6. (F) Tetramer-positive (LCMV-specific) CD8+ T cells in the spleen of bone marrow chimeras 12 days post LCMV-infection. Chimeric mice were generated by transplanting lethally-irradiated wild-type recipients with equal numbers of wild-type and Nlrp1−/− bone marrow cells. *p<0.05, Mean ± SEM, n=4.