Table 1. CD4 expression levels in the spinal cord do not change during CIPN.
No significant changes were detected in the expression levels of CD4 within the dorsal spinal cord of oxaliplatin-treated rats at a time-point of peak mechano-hypersensitivity (D25). Results are analyzed by Student’s t-test (Ct) and expressed as fold change as compared to vehicle for n=5 rats/group.
| Group | Gene | Ct (Mean ± SD) | n-value | Fold-change |
|---|---|---|---|---|
| Vehicle | CD4 | 24.4 ± 2.09 | 5 | |
| HPRT1 | 19.3 ± 0.200 | |||
| Oxaliplatin | CD4 | 23.9 ± 1.24 | 5 | 0.693 |
| HPRT1 | 19.1 ± 0.190 |