Table-2. Effects of 6 RSD cycles on dependent variables of body weight, splenic mass and CCL2 mRNA expression in splenic macrophages (n = 8 – 9/group).
Dependent variable | Control | RSD | two-tailed p value |
---|---|---|---|
| |||
Body weight (g) | 23.65 ± 0.38 | 25.28 ± 0.65 | 0.0457 |
Splenic mass (mg) | 65.11 ± 1.78 (median = 66) | 149.89 ± 6.10 (median = 151) | < 0.0001* |
Ratio of splenic mass to body weight | 0.00275 ± 0.00006 (median = 0.00276) | 0.00598 ± 0.00032 (median = 0.00612) | < 0.0001* |
CCL2 mRNA expression (2-ΔΔCTvalues) | 1.111 ± 0.064 (median = 1.138) | 2.574 ± 0.206 (median = 2.471) | < 0.05* |
Two-tailed unequal variance t-test was used to calculate p values because equal variance F tests for splenic mass, the ratio and CCL2 mRNA expression failed
Data are represented as mean ± standard error of mean