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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Synapse. 2014 Nov 20;69(2):78–85. doi: 10.1002/syn.21790

Figure 3.

Figure 3

Ketanserin blocks 5-HT2C agonist induced attenuation of potassium stimulated GABA release. The concentration of GABA in the dialysate is displayed over time. Grey shaded areas represent perfusion with 50 mM potassium containing aCSF. White bar signifies when 50 μM ketanserin was present. Black bar indicates when 50 μM 5-HT2C receptor agonist was present. (A) Ketanserin alone has no effect on potassium stimulated GABA release. However, when constantly perfused throughout the experiment, ketanserin blocks (B) (−)-trans-PAT, (C) (−)-trans-p-Cl-PAT, and (D) m-Cl-6-OMe-PAT from attenuating potassium stimulated GABA release. The data shown are mean values ± SEMs for n = 3 in each panel. * indicates p < 0.05 by AUC comparison.