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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Am J Obstet Gynecol. 2014 Aug 6;212(1):71.e1–71.e8. doi: 10.1016/j.ajog.2014.07.060

Figure 2. PHT conditioned medium or miRNA mimics from the C19MC attenuate infection of select togaviruses.

Figure 2

(A) Log scale of Rubella virus titers from cells exposed to non-conditioned or conditioned PHT medium. Data are mean of three independent plaque assays, each run in duplicate. p <0.05 (Student's t test). (B) Activity of alphavirus luciferase reporter constructs. Eastern equine encephalitis virus (EEEV), Venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV), and Sindbis virus (SINV), expressing luciferase in Vero cells, were exposed to conditioned PHT or control non-conditioned medium. Data are presented as percent infection relative to control and represent a mean of three independent infections, each run in triplicate. p <0.0001 (ANOVA with Bonferroni correction). (C) EEEV, VEEV, CHIKV, and SINV luciferase expression in cells transfected with miR-517-3p or control scrambled mimic. Data are presented as percent infection relative to control and represent a mean of three independent infections, each run in triplicate. p <0.0001 (ANOVA with Bonferroni correction).

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