Table 3. Base Case Output.
PECARN Rules | Usual Care | Difference a | |
---|---|---|---|
CT scans, n b | 274 | 353 | 79 |
Radiation-induced malignancy | 0.34 | 0.45 | 0.11 |
Missed ciTBI (delayed treatment), n | 0.26 | 0.02 | −0.24 |
Total cost | $904,940 | $954,420 | $49,480 |
Total QALY loss | −4.64 | −5.79 | −1.15 |
QALY loss due to missed ciTBI | −0.92 | −0.99 | −0.07 |
QALY loss due to radiation-induced malignancy | −3.72 | −4.80 | −1.08 |
Incremental cost-effectiveness ratio of usual care, as compared with PECARN rules c | −$43,030 (dominated) | ||
Net monetary benefit of PECARN rules d | $106,980 |
Abbreviations: CT, computed tomography; ciTBI, clinically important traumatic brain injury; QALY, quality-adjusted life year; WTP, willingness-to-pay
- difference = usual care – PECARN rules
- including CT scans for those who return to hospital for ongoing issues
- incremental cost-effectiveness ratio = Δtotal cost / ΔQALY loss
- net monetary benefit = (Δtotal QALY * WTP per QALY) - Δtotal cost. WTP used here is $50,000/QALY.