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. 2015 Jan 5;25(1):8–14. doi: 10.2188/jea.JE20140022

Table 2. Morbidity, mortality, and other variables concerning prion diseases in Japan, by prefecture.

  Populationa
(thousands)
Number of newly diagnosed patients Number of
newly
diagnosed patients
(1999–2011)b
Crude
incidence rate
(per million population/year)
Standardized morbidity ratio
(95% CI)
Number of
fatal patients
(1999–2012)
Crude
mortality rate
(per million population/year)
Standardized mortality ratio
(95% CI)
Total 127 768 2026 1814 1.09   2334 1.30  
 
Hokkaido 5628 138 124 1.69 1.47 (1.23–1.76) 106 1.35 0.97 (0.80–1.18)
Aomori 1437 19 16 0.86 0.72 (0.41–1.16) 20 0.99 0.69 (0.42–1.07)
Iwate 1385 19 19 1.06 0.85 (0.51–1.35) 22 1.13 0.75 (0.47–1.14)
Miyagi 2360 44 43 1.40 1.31 (0.95–1.77) 43 1.30 1.01 (0.73–1.37)
Akita 1146 28 28 1.88 1.40 (0.93–2.03) 32 2.00 1.22 (0.84–1.72)
 
Yamagata 1216 20 20 1.26 1.00 (0.61–1.54) 18 1.06 0.69 (0.41–1.09)
Fukushima 2091 38 35 1.29 1.10 (0.77–1.53) 36 1.23 0.87 (0.61–1.20)
Ibaraki 2975 18 15 0.39 0.36 (0.20–0.59) 35 0.84 0.66 (0.46–0.91)
Tochigi 2017 16 10 0.38 0.36 (0.17–0.66) 40 1.42 1.11 (0.79–1.51)
Gunma 2024 41 39 1.48 1.33 (0.95–1.82) 36 1.27 0.95 (0.67–1.32)
 
Saitama 7054 67 60 0.65 0.66 (0.50–0.85) 119 1.20 1.04 (0.86–1.24)
Chiba 6056 97 85 1.08 1.05 (0.84–1.30) 100 1.18 0.97 (0.79–1.19)
Tokyo 12 577 166 149 0.91 0.90 (0.76–1.06) 228 1.29 1.08 (0.94–1.23)
Kanagawa 8792 154 134 1.17 1.19 (1.00–1.42) 153 1.24 1.07 (0.91–1.26)
Niigata 2431 51 49 1.55 1.28 (0.94–1.68) 53 1.56 1.06 (0.79–1.39)
 
Toyama 1112 12 10 0.69 0.57 (0.27–1.05) 18 1.16 0.79 (0.47–1.25)
Ishikawa 1174 38 35 2.29 2.05 (1.43–2.84) 22 1.34 1.00 (0.63–1.51)
Fukui 822 7 6 0.56 0.48 (0.18–1.05) 7 0.61 0.43 (0.17–0.89)
Yamanashi 885 26 23 2.00 1.77 (1.12–2.65) 32 2.58 1.90 (1.30–2.68)
Nagano 2196 21 19 0.67 0.55 (0.33–0.86) 47 1.53 1.04 (0.77–1.39)
 
Gifu 2107 38 32 1.17 1.04 (0.71–1.46) 38 1.29 0.95 (0.68–1.31)
Shizuoka 3792 71 67 1.36 1.22 (0.95–1.55) 86 1.62 1.21 (0.97–1.51)
Aichi 7255 104 94 1.00 1.01 (0.82–1.23) 121 1.19 1.02 (0.85–1.22)
Mie 1867 35 34 1.40 1.23 (0.85–1.72) 41 1.57 1.15 (0.82–1.56)
Shiga 1380 6 5 0.28 0.28 (0.09–0.65) 24 1.24 1.04 (0.67–1.55)
 
Kyoto 2648 16 14 0.41 0.37 (0.20–0.63) 40 1.08 0.83 (0.59–1.13)
Osaka 8817 109 101 0.88 0.84 (0.68–1.02) 145 1.17 0.94 (0.80–1.11)
Hyogo 5591 61 54 0.74 0.68 (0.51–0.89) 112 1.43 1.10 (0.91–1.33)
Nara 1421 8 7 0.38 0.34 (0.14–0.70) 22 1.11 0.84 (0.53–1.27)
Wakayama 1036 6 6 0.45 0.36 (0.13–0.78) 14 0.97 0.65 (0.35–1.09)
 
Tottori 607 6 4 0.51 0.42 (0.11–1.07) 3 0.35 0.24 (0.05–0.70)
Shimane 742 23 21 2.18 1.66 (1.02–2.53) 28 2.69 1.68 (1.12–2.43)
Okayama 1957 32 30 1.18 1.01 (0.68–1.45) 28 1.02 0.73 (0.49–1.06)
Hiroshima 2877 46 41 1.10 0.98 (0.70–1.33) 51 1.27 0.95 (0.71–1.24)
Yamaguchi 1493 35 32 1.65 1.29 (0.88–1.82) 42 2.01 1.30 (0.94–1.76)
 
Tokushima 810 16 13 1.23 1.00 (0.53–1.70) 9 0.79 0.53 (0.26–1.01)
Kagawa 1012 16 14 1.06 0.89 (0.48–1.49) 20 1.41 0.98 (0.60–1.51)
Ehime 1468 26 25 1.31 1.07 (0.69–1.58) 28 1.36 0.92 (0.61–1.33)
Kochi 796 28 28 2.70 2.10 (1.39–3.04) 23 2.06 1.32 (0.83–1.97)
Fukuoka 5050 120 111 1.69 1.57 (1.30–1.90) 93 1.32 1.03 (0.83–1.26)
 
Saga 866 29 28 2.49 2.15 (1.43–3.12) 19 1.57 1.12 (0.68–1.75)
Nagasaki 1479 27 25 1.30 1.08 (0.70–1.60) 34 1.64 1.13 (0.78–1.59)
Kumamoto 1842 20 17 0.71 0.60 (0.35–0.95) 42 1.63 1.13 (0.81–1.52)
Oita 1210 27 26 1.65 1.34 (0.87–1.96) 26 1.54 1.02 (0.67–1.51)
Miyazaki 1153 14 13 0.87 0.72 (0.38–1.23) 22 1.36 0.94 (0.59–1.42)
 
Kagoshima 1753 32 29 1.27 1.04 (0.70–1.50) 39 1.59 1.07 (0.76–1.46)
Okinawa 1362 25 24 1.36 1.55 (1.00–2.32) 16 0.84 0.81 (0.47–1.32)
 
Unknown   30       1    

CI, confidence interval.

aData from 2005 Census.

bPatients whose address was unknown were excluded.