The effect of early dexamethasone (DEX) treatment on the mean number of binucleate cells (BNCs) in sheep placentomes during pregnancy (combined data of placentome subtypes). Data were analyzed by a full factorial model (MANOVA) with treatment, gender, and dG as factors, followed by a pairwise comparison (Holm Sidak) when main effects were P < .05. Data are presented as mean ± standard error of the mean (SEM) per sheep. MANOVA main effects: age P < .001, treatment P < .05; interaction: dG × treatment P < .05. Post hoc P values <.05 are indicated in figure: different letters indicate significant differences in dG, the star indicates significant differences in treatment. n = numbers of animals analyzed.