Fig. 2.

Analogies of angiotropism with neural crest cell (NCC) migration and pericytes recruitment A. Quail hindgut stained with antibodies to QH1 staining endothelial cells (red), and HNK-1 staining NCC (blue). Note the angiotropism of the NCC migrating along a vessel (v) and the analogy with melanoma angiotropism (Fig. 1). From [27]: Nagy N, Mwizerwa O, Yaniv K, Carmel L, Pieretti-Vanmarcke R et al. (2009) Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signaling. Dev Biol 330 (2):263–72. B. Scanning electron microscopy showing pericytes along the abluminal surface of a microvessel (stars). Note the analogy with angiotropism and pericytic mimicry of tumor cells (Fig. 1). Pictures from pathologyoutlines.com: http://www.pathologyoutlines.com/topic/softtissue3vascnormal.html Author: Nat Pernick; Copyright: (c) 2002–2009, PathologyOutlines.com, Inc.