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. 2014 Dec 8;3(12):e132. doi: 10.1038/oncsis.2014.48

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Copyright © 2014 Macmillan Publishers Limited

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Apoptosis in ATM- and NBS1-deficient cells following FR. (a) Annexin V staining was performed for untreated control cells and cells treated with FR for 21 days. Asterisks indicate a significant increase in annexin V-positive cells compared with control cells. (b) Treatment with KU55933 induced apoptosis in ATM-complemented cells exposed to FR for 31 days. Cells were treated with KU55933 for 48 h. Asterisks indicate a significant increase in annexin V-positive cells compared with cells without KU55933 treatment.