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. 2014 Dec 15;5:5340. doi: 10.1038/ncomms6340

Figure 6. The sugar contacts that maintain IL-18/IL-18Rα/IL-18Rβ.

Figure 6

(a) The N-linked glycans identified from the structure. (b) The N-linked glycosylation in this study. (c) Intramolecular interactions between the carbohydrates on Asn150 and His190 as well as on Asn197 and the D1-D2 loop. (d) Interactions between the N-linked carbohydrates on Asn297 and IL-18. Core-FUC moderately interacts with IL-18 at an ~4 Å distance. (e) Interactions between the N-linked carbohydrates on Asn236 and IL-18Rβ.