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. 2014 Dec 15;5:5340. doi: 10.1038/ncomms6340

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(a) The results of cross-saturation experiments with [²H–¹⁵N]-IL-18/IL-18Rα (forest) and the chemical shift change of [²H–¹⁵N]-IL-18/IL-18Rα on adding IL-18Rβ (orange) are coloured on the crystal structure of IL-18 in complex with IL-18Rα and IL-18Rβ. (b) Superimposition of the IL-18/IL-18Rα/IL-18Rβ crystal structure and the low-resolution SAXS envelope.