Table 1.
Clinical course of hemoglobin, leukocyte and platelet counts, AST, ALT, creatine kinase, LDH, aPTT, prothrombin time, and C-reactive protein after the onset of SFTS.
| Laboratory test (reference range) | Day 4 | Day 7 | Day 8 | Day 9 | Day 10 | Day 13 |
|---|---|---|---|---|---|---|
| Hemoglobin, g/dL (11.5–15.3) | 14.4 | 16.4 | 13.2 | 12.3 | 13.1 | 12.7 |
| Leukocyte, ×103/μL (4–9.5) | 3.0 | 4.9 | 3.9 | 4.2 | 4.2 | 4.4 |
| Neutrophil, % (39–73) | NA | 45 | 32 | 61 | 56 | 59 |
| Lymphocyte, % (19–50) | NA | 36 | 52 | 29 | 35 | 27 |
| Atypical lymphocyte, % (0) | NA | 15 | 3 | 0 | 0 | 0 |
| Erythroblast, cell/100 WBC (0) | NA | 1 | 0 | 0 | 0 | 0 |
| Platelet, ×103/μL (150–400) | 61 | 73 | 79 | 89 | 241 | 431 |
| AST, IU/L (11–35) | 157 | 267 | 192 | 147 | 86 | 42 |
| ALT, IU/L (5–35) | 66 | 122 | 97 | 89 | 82 | 56 |
| Creatine kinase, IU/L (45–235) | 155 | 207 | 127 | 86 | 52 | 31 |
| LDH, IU/L (120–230) | 483 | 577 | 437 | 356 | 284 | 206 |
| aPTT, sec (20–35) | NA | 33.8 | 31.3 | 30.5 | 29.3 | 26.9 |
| Prothrombin time, INR (0.8–1.2) | NA | 0.88 | 0.89 | 0.92 | 0.98 | 1.03 |
| C-reactive protein, mg/dL (0–0.5) | 1.10 | 0.23 | 0.15 | 0.26 | 0.29 | 0.04 |
*Day 1 was onset day. NA: not available; WBC: white blood cell; AST: aspartate aminotransferase; ALT: alanine aminotransferase; LDH: lactate dehydrogenase; aPTT: activated partial prothromboplastin time; INR: international normalized ratio.