FIG. 1.

Schematic illustration of the synthesis and delivery of vesicular stomatitis virus glycoprotein (VSV-G) pseudotyped lentiviral nanocapsules: (I) Surface modification of the lysine group of the envelope protein by NAS; (II) in situ polymerization of monomer (acrylamide), crosslinker (GMA), and targeting agent (acrylamide tailored-cRGD) at the surface of the modified virus; and (III) targeting delivery of the nanovirus to cells. GMA, glycerol dimethacrylate; cRGD, cyclic arginine-glycine-aspartic acid. Color images available online at www.liebertpub.com/hgtb