Figure 3.

(a) Aminated polystyrene ENP. (b) Unmodified polystyrene ENP. The corona-proteins on both ENP surface types were assigned descriptors based on gene ontology annotations for molecular function using ‘generic gene ontology term finder’ (available online). Descriptors were summarized and grouped by similarity using an online tool (REVIGO) and then simplified to show only the group headings. Tile size represents probability of an annotation appearing within a gene set at a frequency greater than would be expected by chance. There is a larger portfolio of adsorbed proteins on unmodified polystyrene ENPs compared with aminated ENPs which show possible enrichment for proteins involved in the reduction of oxygen.