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. 2014 Dec 16;14:204. doi: 10.1186/1471-2466-14-204

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© Moscato et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Agreement between Brüel&Kjær 1312 (eCOBK) and PiCO + Smokerlyzer (eCOPiCO) (Bland Altman plot). The measures taken into account were 102 (3 measurements for each of 34 subjects). The regression line for the mean agreement (Y = −0.3336 X −9.192) is reported. The coefficient of determination R² was ≈ 0.7214 (p = 0.000). The standard deviation of the residuals is 2.2716; there is no significant relationship between the standard deviation of the differences and the average of the two methods (p = 0.165). To consider the repeated measures approach and the non linear relationship between difference and mean, the Limits of Agreement (LOA) was evaluated modelling the variability in the Standard Deviation of the mean difference directly as a function of the level of the measurement.