Table 3.

Relation of ECG abnormalities with CV events: univariable (model 1), and adjusted for SCORE risk factors (model 2)

	ECG abnormalities	Model 1, HR (95% CI)	Model 2,a HR (95% CI)
Lausanne criteria	P-wave
	Left atrial enlargement	b
	Right atrial enlargement	b
	QRS complex
	QRS axis deviation	1.5 (0.8 to 2.7)
	Increased voltage	1.1 (0.2 to 8.1)
	Pathological Q-waves	4.3 (1.6 to 11.6)	2.2 (0.8 to 6.0)
	Right or left bundle branch block	2.6 (0.8 to 8.2)	1.5 (0.5 to 4.8)
	R or R’ wave in lead V1	2.2 (0.3 to 16.0)
	ST-segment, T-waves, and QT-interval
	ST-segment depression, T-wave flattening, or inversion in two or more leads	2.2 (1.2 to 4.2)	1.4 (0.8 to 2.7)
	Prolongation of heart rate-corrected QT interval	1.7 (1.0 to 2.7)	0.9 (0.6 to 1.6)
	Rhythm and conduction abnormalities
	Premature ventricular beats or more severe ventricular arrhythmias	1.6 (0.6 to 3.8)
	Supraventricular tachycardias, atrial flutter, or atrial fibrillation	6.3 (2.3 to 16.9)	4.4 (1.6 to 11.9)
	Short PR interval	0.9 (0.3 to 2.4)
	Sinus bradycardia	b
	First-, second-, or third-degree atrioventricular block	1.7 (0.6 to 4.7)
	Any Lausanne abnormality	1.6 (1.2 to 2.3)	1.2 (0.8 to 1.6)
MEANS diagnosis	Myocardial infarction	3.3 (1.7 to 6.2)	2.3 (1.2 to 4.3)
	Left ventricular hypertrophy	0.5 (0.0 to 16.8)
	Atrial fibrillation/flutter	6.3 (2.3 to 16.9)	4.4 (1.6 to 11.9)
	Left and right bundle branch block	2.6 (0.8 to 8.2)	1.5 (0.5 to 4.8)
	ST-segment and/or T-wave abnormalities	2.1 (1.6 to 4.2)	1.4 (0.8 to 2.7)
	Second and third atrioventricular blocks	4.1 (0.6 to 29.0)

^aCox model (model 1) with a P-value < 0.157 was combined in a more extended multivariable Cox model (model 2).

^bNot calculated as fewer than five individuals.