Figure 1.

Peptide sequences, a schematic of the click reaction, and the half-moon model. A) Peptide sequences used for this study. Key: z, azido norleucine; Prop, propiolate. B) The gel was formed using an N-terminally azido-modified hSAF-p1. Decoration was achieved by performing a click reaction with alk-RGDS on azide-containing gels catalyzed by CuSO₄ with ascorbic acid (AA). C) Side-by-side gel formation in 24-well cell-culture plates allowed a direct comparison of cellular behavior on undecorated hSAF- and RGDS-decorated hSAF gels. Key: undecorated hSAF gel, gray; and RGDS-decorated hSAF gel, blue.