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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Curr Trop Med Rep. 2014 Sep 27;1(4):181–193. doi: 10.1007/s40475-014-0029-4

Table 1b.

Summary of articles published on the effectiveness of community-based control strategies aimed at reducing porcine cysticercosis.

Country
[reference]
Years of
study
Study design Duration of
follow-up
Sample sizes (at the unit of
the intervention and at the
subject level pre and post
intervention
Control Strategy Randomization/
control group
Measurement of
outcome
Mexico [11] 1991-96 Pre-post prevalence
comparison
6 and 42
months
1 village
Tongue: Pre: 646; 6 mo: 449;
42 mo: 334
Serum: Pre: 269; 6 mo: 448; 42
mo: 326
Praziquantel (single dose
5mg/kg) MDA (87%
coverage)
No / No Tongue examination
and EITB
Guatemala [12] 1994-96 Pre-post prevalence
comparison
10 months 2 villages
Pre : 269
Post : 300
Niclosamide MDA (2g for
>= 6 years old, 1 g for < 6
years old; coverage
74.9%)
No / No EITB
Mexico [21] 2001-2003 Pre-post prevalence
comparison in sentinel
pigs during controlled
trial with study pigs
4 to 8 months;
14 and 28
months for
sentinel pigs
One community
Sentinel pigs : Pre : 29; 14 mo :
200; 28 mo : 50
S3Pvac (1 dose at 2
months in 48 study pigs
and 2 doses at 2 and 3
months in 98 study pigs)
No / No (for the
sentinel pigs)
Tongue examination
Mexico [17] Not
specified
Pre-post prevalence
comparison
12 and 24
months
6 villages (12 mo) and 4
villages (24 mo)
Pre (6 villages): 814
Pre (4 villages) : 508
12 mo (6 villages) : 971
24 mo (4 villages) : 655
Vaccine prepared from
crude antigens extracts
No / No Tongue examination
Peru [18] Not
specified
Pre-post community-
based randomized
controlled trial (paired?)
20 months with
examinations
every 4 months
12 “treatment units”, 9 villages One praziquantel MDA
in humans (5mg/kg)
coverage 75%, two
oxfendazole MDA in pigs
(30 mg/kg)
Yes / Yes (one
pyrantel pamoate
MDA in humans (11
mg/kg) coverage
75%; no control MDA
in pigs)
EITB
Mexico [16] 1986-87 Pre-post prevalence
comparison
«about» 1 year 1 village (440 pigs pre and
300? pigs post)
Education (meetings)
* and praziquantel MDA
(60% coverage)
No / No Tongue examination
Tanzania [9] 2002-2004 Pre-post community-
based randomized
controlled trial
2-9 months 42 villages in one district
133 pigs in intervention; 128 in
control
PRECEDE-PROCEED to
develop educational
package for farmers
Yes / Yes(No
education)
Tongue examination
and §AgELISA
Mexico [13] 1992-93 Pre-post prevalence
comparison
6 months 1 village
Pre: 194; Post: 165
Education (6 months):
(poster, pamphlet, two
videos)
No / No Tongue examination
and EITB
Ecuador [21] 1986-87 Pre-post prevalence
comparison
12 months Part of one canton
Pre: 70 pigs; Post: 113 pigs
Education (radio, poster,
leaflet) and praziquantel
(5 mg/kg; 76% coverage)
No / No “careful” inspection
of pigs killed at the
local slaughterhouse
Mexico [27] 2009-2012 Pre-post prevalence
comparison
39 months 3 municipalities (AgELISA: Pre:
1012; post: 180; Tongue: Pre:
960; post: 396; Ultrasound:
Pre: 786; post: 381)
Education (pamphlets,
meetings, videos) and
pig vaccination (3 times
at 6 months interval)
with S3Pvac
None AbELISA, tongue
inspection and
ultrasound.
*

MDA: Mass drug administration

§

AgELISA : Enzyme linked Immunosorbent assay to detect antigens to T. solium

EITB: Enzyme linked immunoelectrotransfer blot assay to detect antibodies to T. solium