Table 3.
Model | Hazard Ratio | 95% Confidence Interval | p-value |
---|---|---|---|
Univariate | 3.33 | 2.57–4.36 | <.0001 |
Multivariate | |||
Adjusted for traditional risk factors* | 2.78 | 2.10–3.72 | <.0001 |
Adjusted for traditional risk factors* + BNP +eGFR** | 2.57 | 1.64–4.15 | <.0001 |
Quartile 1 versus 4; Abbreviations, BNP: brain natriuretic peptide; and eGFR: estimated glomerular filtration rate.
Traditional risk factors including age, gender, systolic blood pressure, history of diabetes, smoking, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol;
Subset of 800 subjects with biomarker data available.