. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Oct 8;90(5):1168–1176. doi: 10.1016/j.ijrobp.2014.08.008

Table 3.

Analysis of local failure for patients receiving a BED₁₀ ≥ 80 (n=108) using competing risks methods.

Factor	Univariate Analysis p-value	Multivariate Analysis final model
Factor	Univariate Analysis p-value	HR (95% CI)	p-value
Age at diagnosis (year), mean ± SD	0.22(HR=1.03)
Male (vs. female)	0.41
> 2cm from PBT (yes vs. no)	0.27
KPS < 80 at diagnosis (yes vs. no)	0.75
Tumor type	0.27
Primary NSCLC
Recurrent NSCLC
Metastatic NSCLC
GTV size (continuous)	0.009(HR=1.62)	1.52 (1.05 - 2.20)	0.03
BED₁₀ (continuous)	0.15 (HR=0.98)
BED₁₀≥100 (yes vs. no)	0.22

Abbreviations: SD, standard deviation; PBT, proximal bronchial tree; KPS, Karnofsky Perfomance Status; NSCLC, Non-small cell lung cancer; GTV, gross tumor volume; BED₁₀, Biologically equivalent dose for α/β = 10; HR, hazard ratio.