Table 1.
Experiment | Treatment Duration | Genotype | Drug | BP | pH | pCO2 | O2 |
---|---|---|---|---|---|---|---|
SD | Chronic | WT | Control | 92±7 | 7.41±0.04 | 28±4 | 132±18 |
WT | Topiramate | 98±9 | 7.34±0.03 | 30±4 | 140±12 | ||
WT | Lamotrigine | 89±7 | 7.37±0.04 | 30±2 | 113±15 | ||
R192Q | Control | 96±5 | 7.38±0.04 | 28±4 | 132±16 | ||
R192Q | Topiramate | 88±7 | 7.33±0.04 | 27±3 | 142±11 | ||
R192Q | Lamotrigine | 95±8 | 7.36±0.03 | 29±2 | 129±13 | ||
Acute | WT | Control | 88±6 | 7.31±0.04 | 32±4 | 134±11 | |
WT | Topiramate | 81±7 | 7.25±0.02 | 34±5 | 153±5 | ||
WT | Lamotrigine | 82±4 | 7.33±0.04 | 34±5 | 137±16 | ||
PID | Chronic | WT | Control | 95±16 | 7.38±0.03 | 38±5 | 122±30 |
WT | Topiramate | 88±11 | 7.37±0.05 | 37±6 | 131±23 | ||
WT | Lamotrigine | 94±10 | 7.40±0.05 | 33±6 | 136±25 | ||
Acute | WT | Control | 92±13 | 7.40±0.04 | 36±3 | 116±13 | |
WT | Topiramate | 82±11 | 7.35±0.07 | 37±6 | 129±12 | ||
WT | Lamotrigine | 85±10 | 7.40±0.04 | 34±6 | 123±25 |
Data are displayed as mean ± standard deviation.