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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Pigment Cell Melanoma Res. 2014 Oct 1;28(1):94–104. doi: 10.1111/pcmr.12315

Figure 1. Flow diagram illustrating the sample sets used for analyses described.

Figure 1

Ulceration status data relating to primary melanoma was available for a total of 1804 patients recruited to the Cohort and SNB studies. Gene expression data were available for 348 individual primary tumors from this patient group. This represents the gene expression test set. The first validation dataset (Leeds replication) consisted of an independent set of 124 primary tumors selected from within the Cohort Study. The second validation data set (Lund replication) consisted of 163 primary melanomas. One hundred and ninety-five tumors from the SNB study were used for IHC staining, 130 of these tumors were also cored for gene expression studies in the test set.