Table 6.

Selected and recent AHF risk-stratification studies determining events within 30-days or less of index ED presentation.

First Author Year	Study Type^*	N	Predicted Outcome	Variables In Final Model
Lassus¹⁵⁵ 2013	I,P	441–4,450 (pooled analysis, total n varied by biomarker evaluated)	30-day and 1-year mortality	ST2, MR-proADM, CRP, NT-proBNP, BNP, MR- proANP in addition to clinical model (age, gender, blood pressure on admission, estimated glomerular filtration rate <60 mL/min/1.73 m2, sodium and hemoglobin levels, and heart rate)
Stiell¹⁵⁶ 2013	E, P	559	30-day death and 14-day serious non-fatal events	h/o TIA/CVA, Vital signs, ECG and lab findings
Lee⁸⁸ 2012	E, R	12,591	7-day mortality	HR, creatinine, BP, O2 sat, Tn, cancer, home metolazone, EMS transport
Peterson¹⁵⁷ 2010	I, R	39,783	In-hospital mortality	Age, SBP, BUN, HR, Na, COPD, nonblack race
Fonarow¹⁵⁸ 2008	I, R	5,791	In-hospital mortality, 60 –90 day mortality or rehospitalization	Pneumonia, cardiac ischemia, worsening renal function
Hsieh¹⁰ 2008	I, R	8,384	Inpatient mortality or serious medical complications, 30-day mortality	pH, pulse, renal function, WBC, glucose, sodium
Abraham¹⁵⁹ 2008	I, R	48,612	In-hospital mortality	Age, HR, SBP, Na, creatinine, HF as primary cause for admission, LVSD
Rohde¹⁶⁰ 2006	I, P	779	In-hospital mortality	Cancer, SBP, creatinine, BUN, Na, age
Diercks⁹⁷ 2006	E, P	499	Stay <24 hours in observation and no 30- day adverse cardiac events	Tn, Systolic BP
Auble⁹⁹ 2005	R	33,533	Inpatient mortality or serious medical complications, 30-day mortality and AHF readmission	pH, pulse, renal function, WBC, glucose, sodium
Fonarow¹⁶¹ 2005	I, R	65,275	In-hospital mortality	BUN, Systolic BP, Creatinine

I = inpatient, E = emergency department patients, R = retrospective, P = prospective BUN= blood urea nitrogen, WBC= white blood cell count, BP= blood pressure, TIA= transient ischemic attack, HR= heart rate, COPD= chronic obstructive pulmonary disease, LVSD= center ventricular systolic dysfunction, CVA= cerebrovascular accident, Tn= troponin, BNP= b-type natriuretic peptide, CRP= C-reactive protein, ANP= atrial natriuretic peptide