Table 2.
Proteins differentially present in the serum of childhood- and adult- onset Crohn’s disease.
| Protein name | Protein symbol | MW | pI | Mascot score | Coverage | Expression levels | |
|---|---|---|---|---|---|---|---|
| childhood | adult | ||||||
| Clusterin | CLUS_HUMAN | 53031.00 | 5.90 | 96 | 34 | 5.55 | 54.3* |
| Apolipoprotein B-100 | APOB_HUMAN | 516651.00 | 6.60 | 352 | 29 | 471.1* | 21.6 |
| Ceruloplasmin | CERU_HUMAN | 122983.00 | 5.40 | 102 | 26 | 123* | 17.3 |
Differentially expressed proteins in all samples of each patient group present with their name and symbol, theoretical pI and molecular weight calculated using the CalPI/MW available on the Swiss-Prot Web site. MASCOT search score, and coverage of each identification are also listed. Score is −10 Log (p), where p is the probability that the observed match is a random event. Scores N55 indicate identity or extensive homology at the p < 0.05 level. Expression levels were calculated in relation to control densities. Expression level >1 indicates overexpression, expression level <1 indicates suppression.
p < 0.005.