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In Vitro Drug metabolism and pharmacokinetics (DMPK) profile of ML382.
| ML382 | |
|---|---|
| In Vitro PK Properties
| |
| Microsome Predicted Hepatic Clearance (mL/min/kg)
| |
| Rat CLHEP | 65.7 |
| Human CLHEP | 15.7 |
|
Percent Free Compound in Plasma | |
| Human PPB | 0.4 |
| Rat PPB | 1.7 |
