Table 4.
ML382 | |
---|---|
In Vitro PK Properties
| |
Microsome Predicted Hepatic Clearance (mL/min/kg)
| |
Rat CLHEP | 65.7 |
Human CLHEP | 15.7 |
Percent Free Compound in Plasma | |
Human PPB | 0.4 |
Rat PPB | 1.7 |
ML382 | |
---|---|
In Vitro PK Properties
| |
Microsome Predicted Hepatic Clearance (mL/min/kg)
| |
Rat CLHEP | 65.7 |
Human CLHEP | 15.7 |
Percent Free Compound in Plasma | |
Human PPB | 0.4 |
Rat PPB | 1.7 |