Fig. 3.

Effects of anantin (Anan, antagonist of natriuretic peptide receptor-A) (black circles) given alone (black squares) co-infused with L-NAME or (black triangles) superimposed on L-NAME (10 μg/kg/min) on changes in a mean arterial pressure, b cortical blood flow, c sodium and d urine excretion. Values are means ± SEM. Upward arrows represent Anan bolus (10 μg/kg) added to L-NAME. Asterisks indicate significantly different from values before L-NAME alone or anantin + L-NAME at P < 0.05 or less