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. 2014 Nov 28;11(12):12283–12303. doi: 10.3390/ijerph111212283

Figure 1.

Figure 1

Required sample size in the absence of population substructure. The sample size is indicated by n. The required sample size to achieve 0.8 power at the significance level α = 10−8 has been calculated as a function of t, the number of time points, and ρ, the correlation between measurements at two different time-points.