Table 8.

Gene × environment interaction effect in the KARE cohort. Interactions of sex with SNPs were tested, and p-values for SNPs with genome-wide significant interaction are listed.

Effect	rs2074356 for HDL			rs11066280 for HDL			rs2074356 for Log(AST)			rs11066280 for Log(AST)			rs12229654 for Log(AST)
	beta	Std.Error	p-value	beta	Std.Error	p-value	beta	Std.Error	p-value	beta	Std.Error	p-value	Beta	Std.Error	p-value
SNP	−4.80	0.62	7.28E − 15	−4.69	0.58	4.60E − 16	−0.13	0.02	5.52E − 13	−0.17	0.02	2.81E − 20	−0.15	0.02	1.32E − 19
sex×SNP	2.26	0.39	4.46E − 09	2.21	0.36	1.06E − 09	0.06	0.01	5.82E − 08	0.08	0.01	8.25E − 12	0.07	0.01	3.24E − 11