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. Author manuscript; available in PMC: 2016 Jan 2.
Published in final edited form as: Mol Biosyst. 2014 Oct 31;11(1):38–59. doi: 10.1039/c4mb00443d

Figure 7.

Figure 7

Structures of enoyl-ACP reductases. Top: FabI from E. coli (PDB: 2FHS), FabL from B. subtilis (PDB: 3OIC) and FabV from X. oryzae (PDB: 3S8M) are all members of the SDR superfamily, utilizing NAD(P)H. Whereas FabI and FabL are tetramers, FabV is a monomer. ClustalOmega was used to generate a sequence identity matrix, including FAS1y (the yeast FAS ER), FAS1h (the human FAS ER) and MER (the human mitochondrial ER). Bottom: The ER dimer in type I FAS from pig (2VZ8) is shown in pink/purple, and FabK from S. pneumoniae (2Z6I).

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