Table 1.
Fatty acid synthase enzymes and their common abbreviations.
Abbrv1 | Abbrv2 | Name | E.c. | Ref |
---|---|---|---|---|
ACP | AcpP | Acyl carrier protein | - | 7–9 |
AcpH | AcpH | ACP phosphodiesterase, ACP hydrolase | 3.1.4.14 | 10 |
AcpS | AcpS | ACP synthase, phosphopantetheinyl transferase | 2.7.8.7 | 11 |
DH | FabA | β-Hydroxydecanoyl-ACP dehydratase II | 5.3.3.14 | 12 |
KS1 | FabB | β-Ketoacyl-ACP synthase I | 4.2.3.14 | 13, 14 |
- | FabC | Acyl carrier protein (old name, found to be AcpP) | - | - |
AT | FabD | Malonyl-CoA:ACP transacylase | 2.3.1.39 | 15 |
AccB | FabE | Biotin carboxyl carrier protein of ACCase | - | 16 |
KS2 | FabF | β-Ketoacyl-ACP synthase II | 2.3.1.179 | 14 |
KR | FabG | β-Ketoacyl-ACP reductase | 1.1.1.100 | 17 |
KS3 | FabH | β-Ketoacyl-ACP synthase III | 2.3.1.180 | 18, 19 |
ER | FabI | Enoyl-ACP reductase I | 1.3.1.9 | 20 |
- | FabJ | Ketoacyl synthase (found to be FabF) | - | 21 |
ER | FabK | Enoyl-ACP reductase II (e.g. Streptococci) | 1.3.1.9 | 22 |
ER | FabL | Enoyl-ACP reductase III (e.g. Bacilli) | 1.3.1.104 | 23 |
- | FabM | cis-3-decenoyl-ACP isomerase | 5.3.3.14 | 24 |
- | FabQ | Dehydratase/isomerase | n/a | 25 |
- | FabR | Transcriptional repressor | - | 26 |
- | FabT | Transcriptional regulator | - | 27 |
ER | FabV | Enoyl-ACP reductase IV (e.g. Vibrii) | 1.3.1.9 | 28 |
DH | FabZ | β-Hydroxyacyl-ACP dehydratase I | 4.2.1.59 | 12 |
TE | FatA/B | Acyl-ACP thioesterase | 3.1.2.14 | 29–32 |