Fig. 2.

The chymotrypsin-like activity of proteasomes measured by the bioluminescent proteasome assay. RAW 264.7 cells (arrow) that were not treated with bortezomib and lipopolysaccharide (100 ng/mL) were used as the reference control to determine statistical significance (^*p<0.01). ^†Means statistically significant with a p-value less than 0.01 when compared with bortezomib at a 25 nM concentration (asterisk). The results are reported as mean±standard error of the mean of three independent experiments in triplicate. RLU, relative luminescent units; LPS, lipopolysaccharide; Bor, bortezomib.