Table 1.

Baseline Characteristics and Clinical Outcomes of Patients with Early Acute Respiratory Distress Syndrome (ARDS) Treated with Prolonged Corticosteroid Treatment

IQR, interquartile range; SAPS3, Simplified Acute Physiology Score 3; SOFA, Sequential Organ Failure Assessment; LIS, lung injury score; OI, oxygenation index; PF ratio, partial pressure of arterial oxygen (PaO₂)/fraction of inspired oxygen (FiO₂) ratio; PEEP, positive end-expiratory pressure; NT pro-BNP, N-terminal pro-B-type natriuretic peptide; CRP, C-reactive protein; BAL, bronchoalveolar lavage; TREM, triggering receptor expressed on myeloid cells; MV, mechanical ventilation; ICU, intensive care unit; CIRCI, critical-illness-related corticosteroid insufficiency; TGF-β, transforming growth factor-β; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α.

^*Defined as weaning from MV within 7 days or improvement in LIS of more than 1 point by study day 7, which was defined as follows: (1) a reduction in LIS ≥1 point, and (2) a day 7 LIS ≤2.0 (for study entry LIS ≤2.9) or ≤2.5 (for study entry LIS ≥3.0).