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. 2014 Oct 21;289(52):36179–36193. doi: 10.1074/jbc.M114.557009

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — Wnt-5a induces mitochondrial dynamics on CA1 region of the hippocampus of rat brain. A, micrographs from electron microscopy show representative slices of CA1 region of hippocampus treated with Wnt-5a in a time course experiment (M, mitochondria) (panel a). B, number of mitochondria in pre- (panel b) and postsynaptic terminals (panel c), respectively, was quantified in response to Wnt-5a treatment; the area of mitochondria from the postsynaptic terminals was measured (panel d), and the percentage of post-synaptic zones containing mitochondria after Wnt-5a stimulus was quantified and compared with baseline (panel e). Quantitative analysis was performed with n = 3, one-way ANOVA, post hoc Bonferroni; *, p < 0.05; **, p < 0.005; ***, < 0.0005. Bar, 500 nm.