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. 2014 Nov 14;289(52):36263–36274. doi: 10.1074/jbc.M114.611020

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — Amino acid sequence relatedness of V. vulnificus Prx3 (VvPrx3) and members of the Prx5 subfamily. The amino acid sequences retrieved from the NCBI protein database (accession numbers: ADV89163 for V. vulnificus Prx3, NP_230994 for the V. vulnificus Prx3 homologue in V. cholerae, 1TP9_A for P. trichocarpa PrxD (PtPrxD), XP_002808799 for P. falciparum AOP (PfAOP), NM_012094 for human Prx5 (HsPrx5)) were aligned using the ClustalW2 program. Identical (asterisks), highly conserved (double dots), conserved (dots), and missing (dashes) sequences are indicated. All cysteine residues are shaded in gray. The positions of the peroxidatic (C_P), second (C₂), and resolving cysteines (C_R) are indicated above the amino acid sequences. The active site PXXXTXXC motifs are indicated by an open box.