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. 2014 Nov 11;289(52):36303–36314. doi: 10.1074/jbc.M114.619569

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Dynamic histomorphometric analysis of trabecular bone in femurs demonstrates increased bone mineralization rate in HMWKO mice. A, fluorescent imaging of calcein and xylenol orange from representative WT and HMWKO mice utilizing a ×5 lens. Smaller image uses a ×20 lens. Dynamic histomorphometry measurements are as follows: B, inter-label thickness. C, mineral apposition rate (MAR). D, mineralizing surface/bone surface (MS/BS), and E, bone formation rate/bone surface (BFR/BS) (n = 9–10). * indicates significantly different from WT (p < 0.05).