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Transcriptional regulation in HMWKO mice favors expression of genes that promote osteoblast differentiation and matrix mineralization in bone. Shown is real time RT-PCR analysis of Col1a1 (A), Runx2 (B), osterix (C), OC (D), Op (E), Dmp1 (F), Phex (G), Mgp (H), Dkk1 (I), and Mepe (J) mRNA expression in flushed tibial bones (n = 7–13). * indicates significantly different from WT (p < 0.05).
