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MIC and MBC of LL-37, mCRAMP, and SMAP29
Antimicrobial activity for GAS was assayed by determination of the minimum concentration of peptide that prevented growth during overnight incubation in 0.5× Todd-Hewitt broth (MIC) and the minimum concentration of peptide that resulted in 99.9% killing after 1 h of incubation in 0.5× phosphate-buffered saline (MBC).
| Peptide | MIC | MBC |
|---|---|---|
| μm | μm | |
| LL-37 | 50 | 20–30 |
| mCRAMP | 12.5 | 20–30 |
| SMAP 29 | 12.5–25 | 0.5–1 |
