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. 2014 Dec 17;7(12):1069–1090. doi: 10.3390/ph7121069

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Anilino enaminones depress the spiking activity of mitral cells. (A) Normalized bar graph shows inhibition of spiking of mitral cells in response to bath application of KRS-5Me-4-OCF₃ (20 μM), KRS-5Me-3Cl (20 μM), and KRS-5Me-4F (20 μM). Responses to enaminones are normalized with respect to control conditions (* p < 0.05, *** p < 0.001). (B) Original recording from a representative mitral cell illustrates the inhibition in firing rate and hyperpolarization following application of KRS-5Me-4-OCF₃. From [18].