Table 3.

Overall population toxicity.

Toxicity	Events(No. of Patients, %)	WHO grade (No. of Patients, %)
		Grade 1	Grade 2	Grade 3	Grade 4
Rash	31 (44.3%)	8 (11.4%)	18 (25.7%)	4 (5.7%)	1 (1.4%)
Asthenia	18 (25.7%)	8 (11.4%)	7 (10%)	3 (4.3%)	0
Anorexia	15 (21.4%)	9 (12.9%)	5 (7.1%)	1 (1.4%)	0
Diarrhea	12 (17.1%)	7 (10%)	0	5 (7.1%)	0
Dyspnea	8 (11.4%)	6 (8.6%)	2 (2.9%)	0	0
Transaminase alteration	4 (5.7%)	3 (4.3%)	0	1 (1.4%)	0
Fever	18 (25.7%)	4 (5.7%)	14 (20%)		0
Fatigue	7 (10%)	0	7 (10%)		0
Arthralgias	4 (5.7%)	0	4 (5.7%)		0