Table 1.
Results of HPV test and Pap cytology on 8461 split cervicovaginal cell samples ordered by private gynecologists in Milford, CT, USA.
| HPV Genotype | No. PAP-Negative | No. PAP-ASCUS | No. PAP-LSIL | No. PAP-HSIL(%) | [(PAP− cases)/(HPV+ cases)] = (%) |
|---|---|---|---|---|---|
| 6 | 17 | 7 | 6 | 0 | 17/30 (56.7) |
| 11 | 1 | 1 | 1 | 0 | 1/3 (33.3) |
| 16 | 55 | 16 | 20 | 22(19.5) | 55/113 (48.7) |
| 18 | 19 | 6 | 11 | 1(2.7) | 19/37 (51.4) |
| 26 | 0 | 0 | 3 | 0 | 0/3 (0) |
| 31 | 15 | 11 | 7 | 5(13.2) | 15/38 (39.5) |
| 32 | 5 | 0 | 0 | 0 | 5/5 (100) |
| 33 | 10 | 4 | 2 | 3(15.8) | 10/19 (52.6) |
| 35 | 13 | 2 | 6 | 2(8.7) | 13/23 (56.5) |
| 39 | 17 | 4 | 8 | 0 | 17/29 (58.6) |
| 40 | 3 | 2 | 0 | 0 | 3/5 (60.0) |
| 44 | 6 | 3 | 0 | 0 | 6/9 (33.3) |
| 45 | 22 | 5 | 3 | 1(3.2) | 22/31 (71.0) |
| 51 | 3 | 0 | 3 | 0 | 3/6 (50.0) |
| 52 | 31 | 7 | 12 | 4(7.4) | 31/54 (57.4) |
| 53 | 5 | 1 | 4 | 0 | 5/10 (50.0) |
| 54 | 40 | 2 | 2 | 0 | 40/44 (90.9) |
| 55 | 4 | 2 | 0 | 0 | 4/6 (66.7) |
| 56 | 9 | 4 | 5 | 0 | 9/18 (50.0) |
| 58 | 15 | 4 | 4 | 0 | 15/23 (65.2) |
| 59 | 18 | 3 | 8 | 1 (3.3) | 18/30 (60.0) |
| 61 | 19 | 4 | 1 | 0 | 19/24 (79.2) |
| 62 | 19 | 0 | 2 | 0 | 19/21 (90.5) |
| 66 | 2 | 3 | 15 | 0 | 2/20 (10.0) |
| 67 | 5 | 3 | 1 | 0 | 5/9 (55.6) |
| 68 | 2 | 0 | 1 | 0 | 2/3 (66.7) |
| 69 | 2 | 1 | 1 | 0 | 2/4 (50.0) |
| 70 | 11 | 0 | 2 | 0 | 11/13 (84.6) |
| 71 | 2 | 0 | 0 | 0 | 2/2 (100) |
| 72 | 17 | 0 | 0 | 0 | 17/17 (100) |
| 73 | 15 | 6 | 6 | 0 | 15/27 (55.6) |
| 74 | 1 | 1 | 0 | 0 | 1/2 (50.0) |
| 81 | 16 | 3 | 7 | 0 | 16/26 (61.5) |
| 83 | 2 | 1 | 0 | 0 | 2/3 (66.7) |
| 84 | 12 | 0 | 0 | 0 | 12/12 (100) |
| 86 | 1 | 0 | 1 | 0 | 1/2 (50.0) |
| 87 | 1 | 1 | 1 | 0 | 1/3 (33.3) |
| 89 | 1 | 0 | 1 | 0 | 1/2 (50.0) |
| 90 | 1 | 0 | 0 | 0 | 1/1 (100) |
| 91 | 1 | 0 | 0 | 0 | 1/1 (100) |
| Mixed | 18 | 17 | 5 | 2 (4.8) | 18/42 (42.9) |
| HPV+ cases Subtotal | 456 | 124 | 149 | 41 | 456/770 (59.2) |
| HPV− cases (PAP− %) | 7545 | 146 | 0 | 0 | 7545/7691 (98.1%) (<LSIL 100%) |
| Total No. | 8001 | 270 | 149 | 41 | 8461 |
Note: The 40 HPV genotypes found in a Southern Connecticut female population in boldfaced numbers are listed in the left column and the 13 high-risk HPV genotypes are underlined. The Pap cytology results classified as Negative, ASCUS, LSIL and HSIL of the split samples of each HPV genotype-positive cases are tabulated on the right to each HPV genotype. The total number of samples positive for each HPV genotype is shown as denominator in the far-right column with the number of Pap negative cases listed as numerator followed by a % in (). The overall % of specimens positive for HPV is 9.1% (770/8461); and 59.2% (456/770) of the HPV-positive samples were negative for Pap cytology. Of the 37 HPV-18 isolates, 30 belonged to the European/Asian American subtypes (Figure 1) and 7 to the African subtype (Figure 2).