Figure 4.
Clustering of the DUX4 construct expressing mouse satellite cell-derived myoblast samples. PCA (a) and hierarchical clustering (b) on the 1000 most variable probes across the five DUX4 constructs and control RV show clustering of technical replicates, demonstrating reproducibility. Note also clustering of tMALDUX4-VP16 (black) with DUX4 (red); DUX4c (green) with tMALDUX4 (yellow) but separation of tMALDUX4-ERD (purple) and control (blue) from other DUX4 constructs.