Table 1.
Maternal & Fetal Characteristics
| Buprenorphine (n=33) M (SD) or f(%) |
Methadone (n=48) M (SD) or f(%) |
F or χ2 | p< | |
|---|---|---|---|---|
| Maternal age in years | 25.0 (5.2) | 27.3 (5.5) | 3.4 | 0.07 |
| Number of pregnancies | 2.2 (0.3) | 2.8 (0.2) | 1.9 | 0.17 |
| Number of living children | 1.5 (0.2) | 1.7 (0.2) | 1.0 | 0.31 |
| Number of OB Visits | 8.8 (2.9) | 8.7 (4.0) | 0.0 | 0.88 |
| Maternal Weight Gain (pounds) | 20.2 (13.3) | 17.5 (17.7) | 0.5 | 0.47 |
| Body Mass Index at enrollment | 24.6 (5.6) | 26.2 (6.8) | 1.2 | 0.28 |
| Systolic Blood Pressure^ | 110.4 (11.4) | 110.7 (9.2) | 0.0 | 0.90 |
| Diastolic Blood Pressure^ | 65.2 (9.1) | 66.1 (8.7) | 0.2 | 0.68 |
| Fundal Height^ | 30.1 (7.1) | 32.0 (1.4) | 2.4 | 0.12 |
| Gestational Age at Fetal Assessment | 31.9 (0.7) | 32.1 (0.6) | 1.2 | 0.28 |
| Gestational age at study entry | 0.1 | 0.83 | ||
| Early (6–21 weeks) | 18 (54.6%) | 25 (52.1%) | ||
| Late (22–30 weeks) | 15 (45.5%) | 23 (47.9%) | ||
| Fetal Sex=Male | 19 (57.6%) | 20 (41.7%) | 1.4 | 0.24 |
| Race | 4.3 | 0.12 | ||
| White | 31 (93.9%) | 41 (85.4%) | ||
| Black | 1 (3%) | 7 (14.6%) | ||
| Other | 1 (3%) | 0 (0%) | ||
| Education | 1.0 | 0.62 | ||
| More than High School | 5 (15.2%) | 7 (14.6%) | ||
| High School Graduate | 11 (33.3%) | 21 (43.8%) | ||
| Less than high school | 17 (51.5%) | 20 (41.7%) | ||
| Employed | 6 (18.2%) | 7 (14.6%) | 0.2 | 0.76 |
| Legal status uninvolved | 29 (87.9%) | 35 (79.9%) | 1.8 | 0.16 |
| Married | 4 (12.1%) | 7 (14.6%) | 0.1 | 0.75 |
| Gestational Diabetes | 0 (0%) | 1 (2.1%) | 0.0 | 0.85 |
| Current cigarette smoker | 31 (93.9%) | 47 (97.9%) | 0.9 | 0.56 |
| Cocaine use prior to enrollment | 7 (21.2%) | 16 (33.3%) | 0.9 | 0.35 |
| Antidepressant | 24 (72.7%) | 32 (66.7%) | 0.1 | 0.74 |
| Anxiolytics | 14 (42.4%) | 13 (27.1%) | 1.4 | 0.23 |
^
Mean of weeks 30–34 of pregnancy; data available for n=30 Buprenorphine and n=47 methadone