Table 5.
First Year of Antiretroviral Therapy | |||||||
---|---|---|---|---|---|---|---|
Mean Cost (95% CI) | Unadjusted | Adjusted | |||||
2006–2008 Cohort (n=186) | 2003–2004 Cohort (n=218) | Cost Difference | p-value | Cost Difference | 95% CI | p-value | |
Medications | |||||||
ART | 13 (2, 25) | 26 (4, 48) | −13 | <0.0001 | −15 | (−16, −13) | <0.0001 |
Non-ART medications | 4 (0, 8) | 6 (0, 20) | −2 | 0.3208 | −2 | (−3, −1) | 0.0004 |
Total medication costs | 17 (4, 30) | 32 (4, 60) | −15 | <0.0001 | −16 | (−18, −14) | <0.0001 |
Laboratory Tests | |||||||
ART Toxicity Monitoring | 2 (0, 5) | 5 (0, 14) | −3 | <0.0001 | −3 | (−4, −3) | <0.0001 |
CD4 cell counts | 3 (0, 7) | 3 (0, 9) | 0 | 0.0207 | 0 | (0, 1) | 0.8448 |
Total Lab Costs | 7 (0, 14) | 13 (0, 33) | −7 | <0.0001 | −7 | (−8, −5) | <0.0001 |
Chest radiographs | 0 (0, 3) | 2 (0, 9) | −1 | <0.0001 | −1 | (−2, −1) | <0.0001 |
Labor Costs | |||||||
Physician | 4 (1, 6) | 4 (0, 10) | 0 | <0.0001 | 0 | (0, 1) | 0.8009 |
Nurse | 0 (0, 1) | 1 (0, 3) | −1 | <0.0001 | −1 | (−1, −1) | <0.0001 |
Pharmacist | 1 (0, 2) | 1 (1, 2) | 0 | 0.0281 | 0 | (−1, 0) | 0.0054 |
Total labor | 6 (2, 9) | 7 (0, 13) | −1 | 0.1525 | −1 | (−2, −1) | <0.0001 |
Overhead | 7 (3, 11) | 10 (5, 15) | −3 | <0.0001 | −3 | (−4, −3) | <0.0001 |
Transportation subsidies | 1 (0, 1) | 1 (0, 1) | 0 | <0.0001 | 0 | (0, 0) | <0.0001 |
Total health system cost | 37 (15, 59) | 64 (17, 112) | −27 | <0.0001 | −29 | (−32, −25) | <0.0001 |
Second Year of Antiretroviral Therapy | |||||||
---|---|---|---|---|---|---|---|
Mean Cost (95% CI) | Unadjusted | Adjusted | |||||
2006–2008 Cohort (n=178) | 2003–2004 Cohort (n=169) | Cost Difference | p-value | Cost Difference | 95% CI | p-value | |
Medications | |||||||
ART | 13 (0, 35) | 33 (2, 65) | −20 | <0.0001 | −22 | (−25, −19) | <0.0001 |
Non-ART medications | 3 (0, 6) | 3 (0, 8) | 0 | 0.6357 | −1 | (−1, 0) | 0.034 |
Total medication costs | 16 (0, 39) | 36 (3, 69) | −20 | <0.0001 | −22 | (−26, −19) | <0.0001 |
Laboratory Tests | |||||||
ART Toxicity Monitoring | 1 (0, 4) | 6 (0, 14) | −5 | <0.0001 | −5 | (−6, −5) | <0.0001 |
CD4 cell counts | 3 (0, 8) | 6 (0, 13) | −4 | <0.0001 | −4 | (−4, −3) | <0.0001 |
Total Lab Costs | 4 (0, 14) | 16 (0, 35) | −12 | <0.0001 | −12 | (−14, −11) | <0.0001 |
Chest radiographs | 0 (0, 2) | 0 (0, 2) | 0 | 0.0869 | 0 | (0, 0) | 0.0376 |
Labor Costs | |||||||
Physician | 2 (0, 4) | 2 (0, 5) | −1 | <0.0001 | −1 | (−0.85, −0.32) | <0.0001 |
Nurse | 0.30 (0, 1) | 1.03 (0, 2) | −1 | <0.0001 | −1 | (−1, −1) | <0.0001 |
Pharmacist | 1 (0, 1) | 1 (1, 2) | 0 | <0.0001 | 0 | (0, 0) | <0.0001 |
Total labor | 3 (0, 6) | 5 (2, 7) | −2 | <0.0001 | −2 | (−2, −2) | <0.0001 |
Overhead | 4 (0, 8) | 9 (5, 12) | −5 | <0.0001 | −5 | (−5, −4) | <0.0001 |
Transportation subsidies | 0 (0, 1) | 1 (0, 1) | 0 | <0.0001 | 0 | (0, 0) | <0.0001 |
Total health system cost | 27 (0, 60) | 67 (25, 109) | −40 | <0.0001 | −42 | (−46, −38) | <0.0001 |