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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: ChemMedChem. 2014 Oct 22;9(12):2653–2660. doi: 10.1002/cmdc.201402398

Table 4.

Functional activity of representative D3 ligands in the quinpirole-induced mitogenesis assay in CHO cells transfected with the human D3 receptor.a

Ligands Agonist activity: IC50 (nM) % of Stimulation compared to Quinpirole as the standard agonist
15 2.0±0.49 100
18 2.0±0.34 100
21 18±2.7 100
23 19±1.5 100
33 17±4.4 100
34 26±4.1 100
a

Data are the mean ± SEM of 3–6 independent determinations.