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. Author manuscript; available in PMC: 2015 Dec 24.
Published in final edited form as: Cell Rep. 2014 Dec 18;9(6):2304–2316. doi: 10.1016/j.celrep.2014.11.042

Figure 6. Comparison of spike waveform properties of genetically and morphologically identified cortical neurons.

Figure 6

(A) Normalized spike waveforms of all genetically and morphologically identified cortical neurons in the PV and SST Cre driver lines compared to putative pyramidal regular spiking cells recorded blindly (range: 350–1100 µm below pia, presumed layers 2/3–6). (B) Cumulative plot of peak-to-trough times of PV and SST subtypes and putative pyramidal cells and (C) comparison of peak-to-trough time and voltage ratios. Note that although PV and regular spiking putative pyramidal cells have narrow and mutually exclusive distributions, SST neurons have widespread and roughly continuous distribution with significant overlap with PV distribution. Also note that while SST spiny bipolar cells (red triangles) are similar to regular spiking cells, PV pyramidal cells (blue triangles) are hardly distinguishable from some PV basket cells (blue squares). Basket, Martinotti, non-Martinotti, spiny bipolar, and pyramidal cells were identified according to morphological criteria (see text). Non-pyramidal cells are histologically confirmed cells lacking apical dendrite and dendritic spines in which not enough axonal information was available for clear morphological assignment. Non-identified cells are histologically confirmed cells where only the soma was recovered.