Table IV.
miR-23b/27b common target genes highly expressed in bladder cancer.
| Clinical BCs | ||||
|---|---|---|---|---|
|
|
||||
| Change | P-value | Entrez gene ID | Symbol | Description |
| 19.55 | 4.67E-05 | 7849 | PAX8 | Paired box 8 |
| 6.79 | 1.14E-04 | 1021 | CDK6 | Cyclin-dependent kinase 6 |
| 5.98 | 1.64E-04 | 1956 | EGFR | Epidermal growth factor receptor |
| 5.00 | 2.65E-04 | 2034 | EPAS1 | Endothelial PAS domain protein 1 |
| 4.74 | 1.21E-04 | 208 | AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| 4.60 | 5.91E-04 | 2246 | FGF1 | Fibroblast growth factor 1 (acidic) |
| 4.20 | 8.23E-04 | 861 | RUNX1 | Runt-related transcription factor 1 |
| 3.96 | 3.16E-03 | 2250 | FGF5 | Fibroblast growth factor 5 |
| 3.91 | 3.75E-04 | 7170 | TPM3 | Tropomyosin 3 |
| 3.75 | 4.46E-04 | 4089 | SMAD4 | SMAD family member 4 |
| 3.75 | 5.59E-04 | 3918 | LAMC2 | Laminin, γ 2 |
| 3.42 | 7.80E-05 | 862 | RUNX1T1 | Runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| 3.31 | 6.45E-05 | 5979 | RET | Ret proto-oncogene |
| 3.09 | 1.75E-02 | 4286 | MITF | Microphthalmia-associated transcription factor |
| 2.87 | 8.69E-04 | 4233 | c-Met | Met proto-oncogene |
| 2.83 | 1.15E-02 | 2259 | FGF14 | Fibroblast growth factor 14 |
| 2.83 | 1.14E-04 | 3845 | KRAS | Kirsten rat sarcoma viral oncogene homolog |
| 2.68 | 2.32E-02 | 7188 | TRAF5 | TNF receptor-associated factor 5 |
| 2.63 | 2.73E-03 | 2932 | GSK3B | Glycogen synthase kinase 3 β |
| 2.60 | 1.82E-03 | 5594 | MAPK1 | Mitogen-activated protein kinase 1 |
| 2.40 | 1.48E-03 | 4193 | MDM2 | MDM2 oncogene, E3 ubiquitin protein ligase |
| 2.37 | 1.40E-03 | 5579 | PRKCB | Protein kinase C, β |